7 Nootropics that are the Real Smart Drugs (According to Lincoln Cannon over at ieet.org)

7 Nootropics that are the Real Smart Drugs


According to Lincoln Cannon over at ieet.org, nootropics – drugs, supplements and foods that enhance cognitive functions – based on peer reviewed scientific research and personal accounts gathered from popular “noot” discussion boards, the best of the rest can be whittled down to these 7:

1. Bacopa Monnieri


Key benefits may lead to:

Improved memory and decreased anxiety, depression and forgetfulness

A key building block of the neurotransmitter serotonin, it has been used for generations in Ayurvedic medicine to improve memory and cognition with double blinded human trials showing that it can decrease anxiety and improve memory. Source 1


2. Creatine


Key benefits may lead to:

Notable decrease to fatigue, improved strength training and possible decrease to depressive episodes and symptoms of sleep deprivation with minor increase to fatigue resistance, subjective well-being, and cognition. Source 2


3. Ginkgo Biloba

Key benefits may lead to:Ginkgo Biloba

Advanced memory, anxiety-reducing and learning abilities

Native to China, 2 vigorous double-blinded clinical trials concluded it may contribute to notable decrease to cognitive decline. Source 3

Young healthy volunteers (Kennedy, 2000 http://www.ncbi.nlm.nih.gov/pubmed/11026748) showed a minor increase to memory, cognition, sleep quality, processing speed, calmness, cerebral blood flow, subjective well-being, processing accuracy and reaction time.Minor decreases were also detected to symptoms of Alzheimer’s, PMS, anxiety, ADHD in children, numerical memory, stress and symptoms of schizophrenia.


4. Myo-inositol


Key benefits may lead to:

Vital for health, Myo-inositol is a small molecule structurally similar to glucose that is involved in cellular signalling and may contribute to notable reduction in anxiety and panic attacks. Source 4


5. Melatonin

Key benefits may lead to:Melatonin

Lower levels of insomnia and a decrease in repercussions of jet lag and improved sleep, memory and clarity.

In animals melatonin is a hormone that anticipates the daily onset of darkness leading to sleepiness and as sleep is essential to recuperating your overall health each day, maintaining an excellent sleeping pattern is essential.


6. Rhodiola Rosea

Key benefits may lead to:Rhodiola Rosea

Less fatigue, increased oxygen uptake, improved cardiac healthand normalized serotonin levels

Deployed as an aid to fight fatigue in South East Asia for centuries, a perennial flowering plant that grows also in cold rugged regions, supplementation may provide a notable decrease to fatigue, increase to subjective well-being, a notable decrease to depression, a minor increase to processing accuracy, and a minor drop in rate of perceived exertion plus stress.


7. Theanine

Key benefits may lead to:

Calm without diminished alertness, plTheanineus decrease to anxiety, symptoms of schizophrenia and minor increase in sleep quality

Without causing sedation, Theanine has also been shown to reduce cortisol, the stress hormone in humans as seen here.

In animal trials as seen here it’s shown to improve mild cognitive impairment and attention spans plus contribute to longevity. Source 5


Bottom line:

These 7 are a pretty decent and typical stack after the big 6 of diet, exercise, sleep, meditation, fasting and standing.

However inositol might help with panic disorders and OCD, but as a smart drug it may as well be inert and probably best used as filler.


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