How to know what type of Nootropic to take?

How to now what type of Nootropic to take?


With several types of nootropics on the market, it’s important to fully understand how your specific choice of these should perform prior to using.

Essentially, all nootropics share the same underlying function – they influence systems and chemicals in the brain that should make them more effective.

There are however inherent risks in using these new brain enhancing supplements so it’s important to understand how neurotransmitters and receptors function upstairs.

How Neurotransmitters and Receptors Operate

Neurotransmitters are chemicals that allow nerve cells (neurons) in the brain to speak to each other.

With these diverse range of chemicals binding to the receptors, they activate each of these neurons allowing them to carry out their specific actions around the body.

Nootropics are designed to enhance the proficiency of these processes.

In turn, this should improve cognitive function – cerebral activities that lead to knowledge, depending on the specific action that is being targeted.


Systems that Nootropics Target


  1. Glutamate – Glutamatergic System


  • Mood
  • Brain health
  • Learning
  • Memory

Glutamate is directly related to how positive you feel so when glutamate is converted to GABA – another of the brains neurotransmitters, it improves your brains health and subsequently mood.

Maintaining the right levels of glutamate though is essential.#

Too low or too high, conditions like autism, ADHD, Alzheimer’s disease and Parkinson’s disease are believed to be attributed to this.

To increase your glutamate uptake, nootropics such as racetams, peptides and ampakines help stimulate receptor sites known as AMPA and NMDA.

This has the double benefit of helping protect you from these future ailments as outlined while improving your current state of mind in focus, memory, mood and energy expended.

  1. Acetylcholine – The Cholinergic System


Sensory perception

Given that you consume a wonderfully healthy diet, acetylcholine in the brain should be plentiful.

Here are 2 types of choline in Nootropics that support the development of acetylcholine in the brain.

  • Alpha GPC

  • Citicholine

Although there is evidence to suggest that when these two are used just on their own, the results aren’t  terrific.

However more recent types of nootropics now combine these two types of choline with other nootropics known as racetams for much improved results. These come in the names of:


Racetams advance the brains synapses related to acetylcholine but do not produce anymore of this neurotransmitter.

Therefore by combining with a choline such as Alpha GPC you are increasing the function of neurotransmitters and their role with working with the synapses in the brain.

  1. Serotonergic and Dopaminergic Systems



Nootropics aren’t as effective at targeting serotonin and dopamine levels as they are with other chemicals in the brain, but these levels are influenced by nootropics supplements in the shape of focus, motivation, mood, reward and memory.

Avoid smart drugs specifically Adderall and Ritalin which are designed to improve serotonin and dopamine levels as they may become addictive, although they do solely target pleasure and happiness levels, so should this be your sole requirement, while more effective at enhancing pleasure and happiness, tread with caution.

Alternatively there are other supplements that directly address serotonin receptors which aren’t addictive but also aren’t strictly classified as nootropics.

Recently it should be noted that there are now new nootropics that will affect dopamine and serotonin receptors but not as considerably as they do acetylcholine or glutamate.

Bottom line:

Now knowing the above and what systems and chemicals different nootropics target in the brain should give you a clearer insight into what specific action you are looking to enhance and improve.

Always read thoroughly about your potential choice of nootropics before taking the plunge in attempting to improve your overall wellbeing.


Leave a Comment